The research on New York State’s opioid crisis, conducted by faculty and students at Colgate in collaboration with the Bassett Research Institute in Cooperstown, will be published in the journal “Drug and Alcohol Dependence.” This article looks at the research on prescribing patterns and opioid overdose morbidity in New York from 2010 through the second quarter of 2016, before mandatory use of the state’s controlled substances database began in August 2013. The research project looked at morbidity (complications and health effects) from overdoses, not mortality, because the numbers are much bigger.